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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACO1
All Species:
9.09
Human Site:
T628
Identified Species:
14.29
UniProt:
P21399
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21399
NP_002188.1
889
98399
T628
E
S
W
N
A
L
A
T
P
S
D
K
L
F
F
Chimpanzee
Pan troglodytes
XP_001155934
889
98362
T628
E
S
W
N
A
L
A
T
P
S
D
K
L
F
F
Rhesus Macaque
Macaca mulatta
XP_001103675
889
98487
T628
E
S
W
N
A
L
A
T
P
S
D
K
L
F
F
Dog
Lupus familis
XP_538698
889
98299
A628
E
S
W
N
A
L
A
A
P
S
D
K
L
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
P28271
889
98160
A628
K
S
W
N
A
L
A
A
P
S
E
K
L
Y
A
Rat
Rattus norvegicus
Q63270
889
98109
A628
K
S
W
N
A
L
A
A
P
S
E
K
L
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509375
889
98624
A628
E
S
W
N
A
L
N
A
P
S
D
K
L
Y
S
Chicken
Gallus gallus
Q90875
889
98055
A628
E
A
W
N
A
L
D
A
P
S
D
K
L
Y
T
Frog
Xenopus laevis
Q6NTP2
955
104418
A695
T
R
W
N
L
L
D
A
P
E
S
T
L
F
P
Zebra Danio
Brachydanio rerio
NP_001030155
890
98920
A628
E
R
W
N
S
L
K
A
P
S
D
K
L
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
V638
Q
D
W
Q
T
L
Q
V
S
E
G
K
L
F
S
Honey Bee
Apis mellifera
XP_392993
890
98796
A630
S
N
W
A
N
L
V
A
P
D
G
K
L
Y
P
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
C626
T
E
W
Q
Q
L
E
C
P
A
V
K
L
Y
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SIB9
990
108183
V724
P
M
W
N
K
L
S
V
P
E
N
T
L
Y
S
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
N517
K
L
K
D
K
D
G
N
E
F
M
L
K
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.9
93.2
N.A.
93.4
92.9
N.A.
90.4
87.5
55.7
82.2
N.A.
67.9
69.4
62.9
N.A.
Protein Similarity:
100
100
99.5
96.9
N.A.
97.7
97.7
N.A.
95.1
93.8
72.2
92
N.A.
82.1
82.5
77.1
N.A.
P-Site Identity:
100
100
100
80
N.A.
66.6
66.6
N.A.
73.3
66.6
40
60
N.A.
33.3
33.3
33.3
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
80
80
40
73.3
N.A.
40
46.6
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.6
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.6
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
54
0
40
54
0
7
0
0
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
0
7
0
7
0
7
14
0
0
7
47
0
0
0
0
% D
% Glu:
47
7
0
0
0
0
7
0
7
20
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
34
20
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
14
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
7
0
14
0
7
0
0
0
0
80
7
0
0
% K
% Leu:
0
7
0
0
7
94
0
0
0
0
0
7
94
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
74
7
0
7
7
0
0
7
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
87
0
0
0
0
7
27
% P
% Gln:
7
0
0
14
7
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
47
0
0
7
0
7
0
7
60
7
0
0
0
20
% S
% Thr:
14
0
0
0
7
0
0
20
0
0
0
14
0
0
14
% T
% Val:
0
0
0
0
0
0
7
14
0
0
7
0
0
0
0
% V
% Trp:
0
0
94
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _